Targeting androgen receptor and PIP5K1A in prostate cancer cells using CRISPR-Cas9 genome editing tool

According to the World Cancer Research statistics, Prostate Cancer (PCa) accounts for 15% of all new cancer cases in men every year. More than 30% of treated patients will suffer disease recurrence and will develop Castration Resistant Prostate Cancer (CRPC), which no longer responds to androgen dep...

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Bibliographic Details
Main Author: Hernández-Quiles, Miguel
Format: Thesis (University of Nottingham only)
Language:English
Published: 2017
Online Access:https://eprints.nottingham.ac.uk/39866/