In vitro amplification of H-type atypical bovine spongiform encephalopathy by protein misfolding cyclic amplification

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In vitro amplification of H-type atypical bovine spongiform encephalopathy by protein misfolding cyclic amplification

The in vitro amplification of prions by serial protein misfolding cyclic amplification has been shown to detect PrPSc to levels at least as sensitive as rodent bioassay but in a fraction of the time. Bovine spongiform encephalopathy is a zoonotic prion disease in cattle and has been shown to occur i...

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Bibliographic Details
Main Authors:	O'Connor, M.J., Bishop, Keith, Workman, Robert G., Maddison, Ben C., Gough, Kevin C.
Format:	Article
Published:	Taylor & Francis 2017
Subjects:	Atypical prions Bovine spongiform encephalopathy H-type BSE PMCA
Online Access:	https://eprints.nottingham.ac.uk/39831/

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