Unravelling the genome-wide contributions of specific 2-alkyl-4-quinolones and PqsE to quorum sensing in Pseudomonas aeruginosa

The pqs quorum sensing (QS) system is crucial for Pseudomonas aeruginosa virulence both in vitro and in animal models of infection and is considered an ideal target for the development of anti-virulence agents. However, the precise role played by each individual component of this complex QS circuit...

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Bibliographic Details
Main Authors: Rampioni, Giordano, Falcone, Marilena, Heeb, Stephan, Frangipani, Emanuela, Fletcher, Matthew P., Dubern, Jean-Frédéric, Visca, Paolo, Leoni, Levi, Cámara, Miguel, Williams, Paul
Format: Article
Published: Public Library of Science 2016
Online Access:https://eprints.nottingham.ac.uk/39814/