Mouse and human genetic analyses associate Kalirin with ventral striatal activation during impulsivity and with alcohol misuse

Mouse and human genetic analyses associate Kalirin with ventral striatal activation during impulsivity and with alcohol misuse

Impulsivity is associated with a spectrum of psychiatric disorders including drug addiction. To investigate genetic associations with impulsivity and initiation of drug taking, we took a two-step approach. First, we identified genes whose expression level in prefrontal cortex, striatum and accumbens...

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Main Authors: Peña-Oliver, Yolanda, Carvalho, Fabiana M., Sanchez-Roige, Sandra, Quinlan, Erin Burke, Jia, Tianye, Walker-Tilley, Tom, Rulten, Stuart L., Pearl, Frances M. G., Banaschewski, Tobias, Barker, Gareth J., Bokde, Arun L. W., Büchel, Christian, Conrod, Patricia J., Flor, Herta, Gallinat, Jürgen, Garavan, Hugh, Heinz, Andreas, Gowland, Penny A., Paillere Martinot, Marie-Laure, Paus, Tomáš, Rietschel, Marcella, Robbins, Trevor W., Smolka, Michael N., Schumann, Gunter, Stephens, David N.
Format: Article
Published: Frontiers Media 2016
Subjects:
impulsivity
binge drinking
adolescent
fMRI
BXD recombinant inbred strains
monetary incentive delay
5-choice serial reaction time task
Online Access:https://eprints.nottingham.ac.uk/39588/

Internet

https://eprints.nottingham.ac.uk/39588/

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