Imaging the kidney using magnetic resonance techniques: structure to function
Purpose of review Magnetic resonance imaging (MRI) offers the possibility to non-invasively assess both the structure and function of the kidney in a single MR scan session. This review summarises recent advancements in functional renal MRI techniques, with a particular focus on their clinical rele...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Published: |
Lippincott, Williams & Wilkins
2016
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/39487/ |
| _version_ | 1848795848571355136 |
|---|---|
| author | Mahmoud, Huda Buchanan, Charlotte Francis, Susan T. Selby, Nicholas M. |
| author_facet | Mahmoud, Huda Buchanan, Charlotte Francis, Susan T. Selby, Nicholas M. |
| author_sort | Mahmoud, Huda |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Purpose of review
Magnetic resonance imaging (MRI) offers the possibility to non-invasively assess both the structure and function of the kidney in a single MR scan session. This review summarises recent advancements in functional renal MRI techniques, with a particular focus on their clinical relevance.
Recent findings
A number of MRI techniques have been developed that provide non-invasive measures of relevance to the pathophysiology of kidney disease. Diffusion-weighted imaging (DWI) has been used in chronic kidney disease (CKD) and renal transplantation, and appears promising as a measure of renal impairment and fibrosis. Longitudinal relaxation time (T1) mapping has been utilised in cardiac MRI to measure fibrosis and oedema; recent work suggests its potential for assessment of the kidney. Blood oxygen level dependent (BOLD) MRI to measure renal oxygenation has been extensively studied, but a number of other factors affect results making it hard to draw definite conclusions as to its utility as an independent measure. Phase contrast and arterial spin labelling (ASL) can measure renal artery blood flow and renal perfusion respectively without exogenous contrast, in contrast to dynamic contrast enhanced (DCE) studies. Current data on clinical use of such functional renal MR measures is largely restricted to cross-sectional studies.
Summary
Renal MRI has seen significant recent interest and advances. Current evidence demonstrates its potential, and next steps include wider evaluation of its clinical application. |
| first_indexed | 2025-11-14T19:38:36Z |
| format | Article |
| id | nottingham-39487 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:38:36Z |
| publishDate | 2016 |
| publisher | Lippincott, Williams & Wilkins |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-394872020-05-04T18:14:09Z https://eprints.nottingham.ac.uk/39487/ Imaging the kidney using magnetic resonance techniques: structure to function Mahmoud, Huda Buchanan, Charlotte Francis, Susan T. Selby, Nicholas M. Purpose of review Magnetic resonance imaging (MRI) offers the possibility to non-invasively assess both the structure and function of the kidney in a single MR scan session. This review summarises recent advancements in functional renal MRI techniques, with a particular focus on their clinical relevance. Recent findings A number of MRI techniques have been developed that provide non-invasive measures of relevance to the pathophysiology of kidney disease. Diffusion-weighted imaging (DWI) has been used in chronic kidney disease (CKD) and renal transplantation, and appears promising as a measure of renal impairment and fibrosis. Longitudinal relaxation time (T1) mapping has been utilised in cardiac MRI to measure fibrosis and oedema; recent work suggests its potential for assessment of the kidney. Blood oxygen level dependent (BOLD) MRI to measure renal oxygenation has been extensively studied, but a number of other factors affect results making it hard to draw definite conclusions as to its utility as an independent measure. Phase contrast and arterial spin labelling (ASL) can measure renal artery blood flow and renal perfusion respectively without exogenous contrast, in contrast to dynamic contrast enhanced (DCE) studies. Current data on clinical use of such functional renal MR measures is largely restricted to cross-sectional studies. Summary Renal MRI has seen significant recent interest and advances. Current evidence demonstrates its potential, and next steps include wider evaluation of its clinical application. Lippincott, Williams & Wilkins 2016-11-01 Article PeerReviewed Mahmoud, Huda, Buchanan, Charlotte, Francis, Susan T. and Selby, Nicholas M. (2016) Imaging the kidney using magnetic resonance techniques: structure to function. Current Opinion in Nephrology and Hypertension, 25 (6). pp. 487-493. ISSN 1473-6543 Magnetic resonance imaging diffusion-weighted imaging diffusion-tensor imaging blood oxygen level dependent MRI arterial spin labelling dynamic contrast enhanced MRI chronic kidney disease acute kidney injury transplantation doi:10.1097/MNH.0000000000000266 doi:10.1097/MNH.0000000000000266 |
| spellingShingle | Magnetic resonance imaging diffusion-weighted imaging diffusion-tensor imaging blood oxygen level dependent MRI arterial spin labelling dynamic contrast enhanced MRI chronic kidney disease acute kidney injury transplantation Mahmoud, Huda Buchanan, Charlotte Francis, Susan T. Selby, Nicholas M. Imaging the kidney using magnetic resonance techniques: structure to function |
| title | Imaging the kidney using magnetic resonance techniques: structure to function |
| title_full | Imaging the kidney using magnetic resonance techniques: structure to function |
| title_fullStr | Imaging the kidney using magnetic resonance techniques: structure to function |
| title_full_unstemmed | Imaging the kidney using magnetic resonance techniques: structure to function |
| title_short | Imaging the kidney using magnetic resonance techniques: structure to function |
| title_sort | imaging the kidney using magnetic resonance techniques: structure to function |
| topic | Magnetic resonance imaging diffusion-weighted imaging diffusion-tensor imaging blood oxygen level dependent MRI arterial spin labelling dynamic contrast enhanced MRI chronic kidney disease acute kidney injury transplantation |
| url | https://eprints.nottingham.ac.uk/39487/ https://eprints.nottingham.ac.uk/39487/ |