Targeting BCL11A/nuclear receptor complexes in breast tumour cells using CRISPR-Cas9 genome editing tool
Many breast cancer patients can respond well to therapies that target Estrogen Receptor, Progesterone Receptor and Human Epidermal Growth Factor 2 (HER-2). However, a proportion of patients (15%) lack expression of these proteins, the so-called triple negative breast cancers (TNBC). TNBC tumours ari...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2017
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| Online Access: | https://eprints.nottingham.ac.uk/39482/ |