Specialised information processing deficits and distinct metabolomics profiles following TM-domain disruption of Nrg1

Specialised information processing deficits and distinct metabolomics profiles following TM-domain disruption of Nrg1

While there is considerable genetic and pathologic evidence for an association between neuregulin 1 (NRG1) dysregulation and schizophrenia, the underlying molecular and cellular mechanisms remain unclear. Mutant mice containing disruption of the transmembrane (TM) domain of the NRG1 gene constitute...

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Bibliographic Details
Main Authors: O'Tuathaigh, C.M.P., Mathur, N., O'Callaghan, M.J., MacIntyre, L., Harvey, R., Lai, D., Waddington, J.L., Pickard, B.S., Watson, D.G., Moran, Paula M.
Format: Article
Published: Oxford University Press 2017
Subjects:
Mutant Phenotype
Cognition
Metabolome
Antipsychotics
Neuregulin
Pre-pulse inhibition
Choline
Lipids
Schizophrenia
Online Access:https://eprints.nottingham.ac.uk/39462/

Internet

https://eprints.nottingham.ac.uk/39462/

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