m6A potentiates Sxl alternative pre-mRNA splicing for robust Drosophila sex determination

m6A potentiates Sxl alternative pre-mRNA splicing for robust Drosophila sex determination

N6-methyladenosine (m6A) is the most common internal modification of eukaryotic messenger RNA (mRNA) and is decoded by YTH domain proteins1, 2, 3, 4, 5, 6, 7. The mammalian mRNA m6A methylosome is a complex of nuclear proteins that includes METTL3 (methyltransferase-like 3), METTL14, WTAP (Wilms tum...

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Bibliographic Details
Main Authors: Haussmann, Irmgard U., Bodi, Zsuzsanna, Sanchez-Moran, Eugenio, Mongan, Nigel P., Archer, Nathan, Fray, Rupert G., Soller, Matthias
Format: Article
Published: Nature Publishing Group 2016
Subjects:
differentiation
alternative splicing
RNA modification
Online Access:https://eprints.nottingham.ac.uk/39448/

Internet

https://eprints.nottingham.ac.uk/39448/

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