Cytoplasmic cyclin E predicts recurrence in patients with breast cancer

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Cytoplasmic cyclin E predicts recurrence in patients with breast cancer

Background: Low-molecular-weight-cyclin E (LMW-E) detected by Western blot, predicts for reduced breast cancer survival, however, it is impractical for clinical use. LMW-E lacks a nuclear localization signal which leads to accumulation in the cytoplasm that can be detected by immunohistochemistry. W...

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Bibliographic Details
Main Authors:	Hunt, Kelly K., Karakas, Cansu, Ha, Min Jin, Biernacka, Anna, Yi, Min, Sahin, Aysegul, Adjapong, Opoku, Hortobogyi, Gabriel N., Bondy, Melissa L., Thompson, Patricia A., Cheung, Kwok-Leung, Ellis, Ian O., Bacus, Sarah, Symmans, W. Fraser, Do, Kim-Anh, Keyomarsi, Khandan
Format:	Article
Published:	American Association for Cancer Research 2016
Subjects:	Cytoplasmic cyclin E breast cancer biomarker cell cycle
Online Access:	https://eprints.nottingham.ac.uk/39211/

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