Cytoplasmic cyclin E predicts recurrence in patients with breast cancer

Cytoplasmic cyclin E predicts recurrence in patients with breast cancer

Background: Low-molecular-weight-cyclin E (LMW-E) detected by Western blot, predicts for reduced breast cancer survival, however, it is impractical for clinical use. LMW-E lacks a nuclear localization signal which leads to accumulation in the cytoplasm that can be detected by immunohistochemistry. W...

Full description

Bibliographic Details
Main Authors: Hunt, Kelly K., Karakas, Cansu, Ha, Min Jin, Biernacka, Anna, Yi, Min, Sahin, Aysegul, Adjapong, Opoku, Hortobogyi, Gabriel N., Bondy, Melissa L., Thompson, Patricia A., Cheung, Kwok-Leung, Ellis, Ian O., Bacus, Sarah, Symmans, W. Fraser, Do, Kim-Anh, Keyomarsi, Khandan
Format: Article
Published: American Association for Cancer Research 2016
Subjects:
Cytoplasmic cyclin E
breast cancer
biomarker
cell cycle
Online Access:https://eprints.nottingham.ac.uk/39211/

Internet

https://eprints.nottingham.ac.uk/39211/

Similar Items