Induction of DNA complexes by type I and type II interferons

The Interferon (IFN) family is divided into two mainly classes which is type I IFN and type II IFN. Type I IFNs activate phosphorylation of STAT1 and STAT2 and induces their heterodimerization and association with IRF9 to form IFN-stimulated gene factor 3 (ISGF3) complex that binds to IFN-stimulated...

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Bibliographic Details
Main Author: Cheng, Wai Kit
Format: Thesis (University of Nottingham only)
Language:English
Published: 2016
Online Access:https://eprints.nottingham.ac.uk/39050/