Hes3 is expressed in the adult pancreatic islet and regulates gene expression, cell growth, and insulin release

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Hes3 is expressed in the adult pancreatic islet and regulates gene expression, cell growth, and insulin release

The transcription factor Hes3 is a component of a signaling pathway that supports the growth of neural stem cells with profound consequences in neurodegenerative disease models. Here we explored whether Hes3 also regulates pancreatic islet cells. We showed that Hes3 is expressed in human and rodent...

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Bibliographic Details
Main Authors:	Masjkur, Jimmy, Arps-Forker, Carina, Poser, Stephen W., Nikolakopoulou, Polyxeni, Toutouna, Louiza, Chenna, Ramu, Chavakis, Triantafyllos, Chatzigeorgiou, Antonios, Chen, Lan-Sun, Dubrovska, Anna, Choudhary, Pratik, Uphues, Ingo, Mark, Michael, Bornstein, Stefan R., Androutsellis-Theotokis, Andreas
Format:	Article
Published:	American Society for Biochemistry and Molecular Biology 2014
Subjects:	Beta Cell (B-cell) Cell Culture Islet Neural Stem Cell (NSC) Neurodegenerative Disease Neuroprogenitor Cell Notch Pathway Pancreas Parkinson Disease Signal Transduction
Online Access:	https://eprints.nottingham.ac.uk/39005/

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