Hes3 is expressed in the adult pancreatic islet and regulates gene expression, cell growth, and insulin release

Hes3 is expressed in the adult pancreatic islet and regulates gene expression, cell growth, and insulin release

The transcription factor Hes3 is a component of a signaling pathway that supports the growth of neural stem cells with profound consequences in neurodegenerative disease models. Here we explored whether Hes3 also regulates pancreatic islet cells. We showed that Hes3 is expressed in human and rodent...

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Bibliographic Details
Main Authors: Masjkur, Jimmy, Arps-Forker, Carina, Poser, Stephen W., Nikolakopoulou, Polyxeni, Toutouna, Louiza, Chenna, Ramu, Chavakis, Triantafyllos, Chatzigeorgiou, Antonios, Chen, Lan-Sun, Dubrovska, Anna, Choudhary, Pratik, Uphues, Ingo, Mark, Michael, Bornstein, Stefan R., Androutsellis-Theotokis, Andreas
Format: Article
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Beta Cell (B-cell)
Cell Culture
Islet
Neural Stem Cell (NSC)
Neurodegenerative Disease
Neuroprogenitor Cell
Notch Pathway
Pancreas
Parkinson Disease
Signal Transduction
Online Access:https://eprints.nottingham.ac.uk/39005/

Internet

https://eprints.nottingham.ac.uk/39005/

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