Dual role of B7 costimulation in obesity-related nonalcoholic steatohepatitis and metabolic dysregulation

Dual role of B7 costimulation in obesity-related nonalcoholic steatohepatitis and metabolic dysregulation

The low-grade inflammatory state present in obesity contributes to obesity-related metabolic dysregulation, including nonalcoholic steatohepatitis (NASH) and insulin resistance. Intercellular interactions between immune cells or between immune cells and hepatic parenchymal cells contribute to the ex...

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Main Authors: Chatzigeorgiou, Antonios, Chung, Kyoung-Jin, Garcia-Martin, Ruben, Alexaki, Vasileia-Ismini, Klotzsche-von Ameln, Anne, Phieler, Julia, Sprott, David, Kanczkowski, Waldemar, Tzanavari, Theodora, Bdeir, Mohktar, Bergmann, Sibylle, Cartellieri, Marc, Bachmann, Michael, Nikolakopoulou, Polyxeni, Androutsellis-Theotokis, Andreas, Siegert, Gabriele, Bornstein, Stefan R., Muders, Michael H., Boon, Louis, Karalis, Katia P., Lutgens, Esther, Chavakis, Triantafyllos
Format: Article
Published: Wiley 2014
Subjects:
liver steatosis
adipose tissue
regulatory T cells
inflammation
Online Access:https://eprints.nottingham.ac.uk/38993/

Internet

https://eprints.nottingham.ac.uk/38993/

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