Stereoelectronic effects in the reaction of aromatic substrates catalysed by Halomonas elongata transaminase and its mutants

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Stereoelectronic effects in the reaction of aromatic substrates catalysed by Halomonas elongata transaminase and its mutants

A transaminase from Halomonas elongata and four mutants generated by an in silico-based design, were recombinantly produced in E. coli, purified and applied to the amination of mono-substituted aromatic carbonyl-derivatives. While benzaldehyde derivatives resulted excellent substrates, only NO2-acet...

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Bibliographic Details
Main Authors:	Contente, Martina Letizia, Planchestainer, Matteo, Molinari, Francesco, Paradisi, Francesca
Format:	Article
Published:	Royal Society of Chemistry 2016
Online Access:	https://eprints.nottingham.ac.uk/38985/

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