Stereoelectronic effects in the reaction of aromatic substrates catalysed by Halomonas elongata transaminase and its mutants
A transaminase from Halomonas elongata and four mutants generated by an in silico-based design, were recombinantly produced in E. coli, purified and applied to the amination of mono-substituted aromatic carbonyl-derivatives. While benzaldehyde derivatives resulted excellent substrates, only NO2-acet...
| Main Authors: | , , , |
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| Format: | Article |
| Published: |
Royal Society of Chemistry
2016
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| Online Access: | https://eprints.nottingham.ac.uk/38985/ |