Longitudinal in vivo MRI in a Huntington’s disease mouse model: global atrophy in the absence of white matter microstructural damage

Longitudinal in vivo MRI in a Huntington’s disease mouse model: global atrophy in the absence of white matter microstructural damage

Huntington’s disease (HD) is a genetically-determined neurodegenerative disease. Characterising neuropathology in mouse models of HD is commonly restricted to cross-sectional ex vivo analyses, beset by tissue fixation issues. In vivo longitudinal magnetic resonance imaging (MRI) allows for disease p...

Full description

Bibliographic Details
Main Authors: Steventon, Jessica J., Trueman, Rebecca C., Ma, Da, Yhnell, Emma, Bayram-Weston, Zubeyde, Modat, Marc, Cardoso, Jorge, Ourselin, Sebastian, Lythgoe, Mark, Stewart, Andrew J., Rosser, Anne E., Jones, Derek K.
Format: Article
Published: Nature Publishing Group 2016
Online Access:https://eprints.nottingham.ac.uk/38799/

Internet

https://eprints.nottingham.ac.uk/38799/

Similar Items