Reprogramming of the mouse Nanog gene in amphibian oocyte extracts

To induce pluripotency in differentiated cells, it is necessary to remodel the epigenetic marks on the regulatory regions of pluripotency genes to enable their expression. The induction of Nanog expression is crucial for establishing pluripotency. However, the epigenetic mechanisms associated with t...

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Bibliographic Details
Main Author: Bereketoğlu, Sidar
Format: Thesis (University of Nottingham only)
Language:English
Published: 2016
Online Access:https://eprints.nottingham.ac.uk/38790/