In utero exposure to cigarette chemicals induces sex-specific disruption of one-carbon metabolism and DNA methylation in the human fetal liver

In utero exposure to cigarette chemicals induces sex-specific disruption of one-carbon metabolism and DNA methylation in the human fetal liver

Background: Maternal smoking is one of the most important modifiable risk factors for low birthweight, which is strongly associated with increased cardiometabolic disease risk in adulthood. Maternal smoking reduces the levels of the methyl donor vitamin B12 and is associated with altered DNA methyla...

Full description

Bibliographic Details
Main Authors: Drake, Amanda J., O'Shaughnessy, Peter J., Bhattachyrya, Siladitya, Monteiro, Ana, Kerrigan, David, Goetz, Sven, Raab, Andrea, Rhind, Stewart M., Sinclair, Kevin D., Meharg, Andrew A., Feldmann, Jorg, Fowler, Paul A.
Format: Article
Published: BioMed Central 2015
Subjects:
DNA methylation
Liver
Maternal smoking
Vitamin B12
Online Access:https://eprints.nottingham.ac.uk/38472/

Internet

https://eprints.nottingham.ac.uk/38472/

Similar Items