Loss of epithelial Gq and G11 signaling inhibits TGFβ production but promotes IL-33–mediated macrophage polarization and emphysema
Heterotrimeric guanine nucleotide–binding protein (G protein) signaling is a ubiquitous signaling system that links hundreds of G protein–coupled receptors (GPCRs) with four G protein signaling pathways. Two of these pathways, one mediated by Gq and G11 and the other by G12 and G13, are implicated i...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Published: |
American Association for the Advancement of Science
2016
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| Online Access: | https://eprints.nottingham.ac.uk/38458/ |