Biophysical studies of the ligand-affinity & binding of leukocyte integrin Mac-1 I-domain: an open & closed case?

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Biophysical studies of the ligand-affinity & binding of leukocyte integrin Mac-1 I-domain: an open & closed case?

Leukocyte integrin Mac-1 plays an integral role in the innate immune system through its function as a cell adhesion receptor. In this role Mac-1 mediates leukocyte migration during the inflammatory response, an essential element of host defense. To date Mac-1 has over 30 identified ligands, with t...

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Bibliographic Details
Main Author:	Morgan, J.
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2016
Online Access:	https://eprints.nottingham.ac.uk/38380/

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