Biophysical studies of the ligand-affinity & binding of leukocyte integrin Mac-1 I-domain: an open & closed case?
Leukocyte integrin Mac-1 plays an integral role in the innate immune system through its function as a cell adhesion receptor. In this role Mac-1 mediates leukocyte migration during the inflammatory response, an essential element of host defense. To date Mac-1 has over 30 identified ligands, with t...
| Main Author: | |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2016
|
| Online Access: | https://eprints.nottingham.ac.uk/38380/ |