POU2F1 activity regulates HOXD10 and HOXD11 promoting a proliferative and invasive phenotype in head and neck cancer

HOX genes are master regulators of organ morphogenesis and cell differentiation during embryonic development, and continue to be expressed throughout post-natal life. To test the hypothesis that HOX genes are dysregulated in head and neck squamous cell carcinoma (HNSCC) we defined their expression p...

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Bibliographic Details
Main Authors: Sharpe, Daniel J., Orr, Katy S., Moran, Michael, White, Sharon J., McQuaid, Stephen, Lappin, Terence R., Thompson, Alexander, James, Jacqueline A.
Format: Article
Published: Impact Journals 2014
Online Access:https://eprints.nottingham.ac.uk/38073/