Impact of intratumoural heterogeneity on the assessment of Ki67 expression in breast cancer

In breast cancer (BC), the prognostic value of Ki67 expression is well-documented. Intratumoural heterogeneity (ITH) of Ki67 expression is amongst the several technical issues behind the lag of its inclusion into BC prognostic work-up. The immunohistochemical (IHC) expression of anti-Ki67 antibody (...

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Bibliographic Details
Main Authors: Aleskandarany, Mohammed A., Green, Andrew R., Ashankyty, I., Elmouna, A., Diez-Rodriguez, Maria, Nolan, Christopher C., Ellis, Ian O., Rakha, Emad
Format: Article
Published: Springer 2016
Subjects:
Online Access:https://eprints.nottingham.ac.uk/37823/