Low-dose salinomycin induces anti-leukemic responses in AML and MLL

Low-dose salinomycin induces anti-leukemic responses in AML and MLL

Development of anti-cancer drugs towards clinical application is costly and inefficient. Large screens of drugs, efficacious for non-cancer disease, are currently being used to identify candidates for repurposing based on their anti-cancer properties. Here, we show that low-dose salinomycin, a cocci...

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Bibliographic Details
Main Authors: Roulston, Gary D.R., Burt, Charlotte L., Kettyle, Laura M.J., Matchett, Kyle B., Keenan, Heather L., Mulgrew, Nuala M., Ramsey, Joanne M., Dougan, Caoifa, McKiernan, John, Grishagin, Ivan V., Mills, Ken I., Thompson, Alexander
Format: Article
Published: Impact Journals 2016
Subjects:
drug repurposing
salinomycin
anti-leukemia
gene signature
AML/MLL-rearrangements
Online Access:https://eprints.nottingham.ac.uk/37804/

Internet

https://eprints.nottingham.ac.uk/37804/

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