Can human pluripotent stem cell-derived cardiomyocytes advance understanding of muscular dystrophies?

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Can human pluripotent stem cell-derived cardiomyocytes advance understanding of muscular dystrophies?

Muscular dystrophies (MDs) are clinically and molecularly a highly heterogeneous group of single-gene disorders that primarily affect striated muscles. Cardiac disease is present in several MDs where it is an important contributor to morbidity and mortality. Careful monitoring of cardiac issues is n...

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Bibliographic Details
Main Authors:	Kalra, Spandan, Montanaro, Federica, Denning, Chris
Format:	Article
Published:	IOS Press 2016
Subjects:	Human embryonic stem cells human induced pluripotent stem cells Cas9/CRISPR genome editing cardiomyocytes Duchenne muscular dystrophy (DMD) myotonic dystrophy (DM1) disease modelling exon skipping gene therapy
Online Access:	https://eprints.nottingham.ac.uk/37782/

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