Role of calpain in breast cancer and regulation of therapeutic response to targeted treatment

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Role of calpain in breast cancer and regulation of therapeutic response to targeted treatment

The calpain system is a group of intracellular cysteine proteases. Dysregulated calpain activity, or mutation in calpain isoforms, as well as its endogenous inhibitor calpastatin, has been found to play an important role in tumorigenesis. The main aim of the current study is to explore the different...

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Bibliographic Details
Main Author:	Pu, Xuan
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2016
Subjects:	Calpain family members Breast Cancer Molecular subtypes Trastuzumab response Monoclonal antibodies HER2+ cells
Online Access:	https://eprints.nottingham.ac.uk/37664/

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