Role of calpain in breast cancer and regulation of therapeutic response to targeted treatment
The calpain system is a group of intracellular cysteine proteases. Dysregulated calpain activity, or mutation in calpain isoforms, as well as its endogenous inhibitor calpastatin, has been found to play an important role in tumorigenesis. The main aim of the current study is to explore the different...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2016
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| Online Access: | https://eprints.nottingham.ac.uk/37664/ |