Investigating the role of Cten in metastatic colorectal cancer

Cten is upregulated in a number of tumour types and in colorectal cancer (CRC), expression is associated with advanced stage, poor prognosis and distant metastasis. Cten appears to regulate cell motility and it can confer features of stemness although, the knowledge of underlying signalling mechanis...

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Bibliographic Details
Main Author: Thorpe, Hannah
Format: Thesis (University of Nottingham only)
Language:English
Published: 2016
Subjects:
Online Access:https://eprints.nottingham.ac.uk/37599/