Single-cell analysis: visualizing pharmaceutical and metabolite uptake in cells with label-free 3D mass spectrometry imaging
Detecting metabolites and parent compound within a cell type is now a priority for pharmaceutical development. In this context, three-dimensional secondary ion mass spectrometry (SIMS) imaging was used to investigate the cellular uptake of the antiarrhythmic agent amiodarone, a phospholipidosis-indu...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Published: |
American Chemical Society
2015
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| Online Access: | https://eprints.nottingham.ac.uk/37559/ |