Post-transcriptional control of tumor cell autonomous metastatic potential by the CCR4-NOT deadenylase CNOT7

Accumulating evidence supports the role of an aberrant transcriptome as a driver of metastatic potential. Deadenylation is a general regulatory node for post-transcriptional control by microRNAs and other determinants of RNA stability. Previously, we demonstrated that the CCR4-NOT scaffold component...

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Bibliographic Details
Main Authors: Faraji, Farhoud, Hu, Ying, Yang, Howard H., Lee, Maxwell P., Winkler, G. Sebastiaan, Hafner, Markus, Hunter, Kent W.
Format: Article
Published: Public Library of Science 2016
Online Access:https://eprints.nottingham.ac.uk/37556/