Targeting Staphylococcus aureus quorum sensing with nonpeptidic small molecule inhibitors
A series of 3-oxo-C12-HSL, tetramic acid, and tetronic acid analogues were synthesized to gain insights into the structural requirements for quorum sensing inhibition in Staphylococcus aureus. Compounds active against agr were noncompetitive inhibitors of the autoinducing peptide (AIP) activated Agr...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Published: |
American Chemical Society
2014
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| Online Access: | https://eprints.nottingham.ac.uk/37554/ |