An appraisal of the Suzuki cross-coupling reaction for the synthesis of novel fluorescent coumarin derivatives

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An appraisal of the Suzuki cross-coupling reaction for the synthesis of novel fluorescent coumarin derivatives

We report the chemical design and development of 3-aryl-substituted 7-alkoxy-4-methylcoumarins with enhanced fluorogenic properties. The 3-aryl substituents are installed via an optimized Suzuki–Miyaura cross-coupling (SMC) reaction between a 7-alkoxy-3-bromo-4-methylcoumarin and aryl boronic MIDA e...

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Bibliographic Details
Main Authors:	Alhaj Zen, Amer, Aylott, Jonathan W., Chan, Weng C.
Format:	Article
Published:	Elsevier 2014
Subjects:	Coumarin Suzuki cross-coupling Arylboronic MIDA ester Fluorescence
Online Access:	https://eprints.nottingham.ac.uk/37547/

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