A facile approach to tryptophan derivatives for the total synthesis of argyrin analogues

A facile route has been established for the synthesis of indole-substituted (S)-tryptophans from corresponding indoles, which utilizes a chiral auxiliary-facilitated Strecker amino acid synthesis strategy. The chiral auxiliary reagents evaluated were (S)-methylbenzylamine and related derivatives. T...

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Bibliographic Details
Main Authors: Chen, Chou-Hsiung, Genapathy, Sivaneswary, Fischer, Peter M., Chan, Weng C.
Format: Article
Published: Royal Society of Chemistry 2014
Online Access:https://eprints.nottingham.ac.uk/37546/