Static and dynamic stress heterogeneity in a multiscale model of the asthmatic airway wall

Airway hyperresponsiveness (AHR) is a key characteristic of asthma that remains poorly understood. Tidal breathing and deep inspiration ordinarily cause rapid relaxation of airway smooth muscle (ASM) (as demonstrated via application of length fluctuations to tissue strips) and are therefore implicat...

Full description

Bibliographic Details
Main Authors: Hiorns, Jonathan E., Jensen, Oliver E., Brook, Bindi S.
Format: Article
Published: American Physiological Society 2016
Subjects:
Online Access:https://eprints.nottingham.ac.uk/37444/