Targeting DNA repair for personalisation of glioblastoma therapy

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Targeting DNA repair for personalisation of glioblastoma therapy

Background Glioblastomas (GBM) are the most common primary brain tumour in adults in the UK and are associated with a poor prognosis. High expression of MGMT (a direct DNA repair protein) has been shown to decrease response to temozolomide and radiotherapy in GBM. Little, however, is known of t...

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Bibliographic Details
Main Author:	Perry, Christina Joy
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2016
Subjects:	DNA repair Brain tumours Synthetic lethality Treatment
Online Access:	https://eprints.nottingham.ac.uk/36449/

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