Targeting DNA repair for personalisation of glioblastoma therapy
Background Glioblastomas (GBM) are the most common primary brain tumour in adults in the UK and are associated with a poor prognosis. High expression of MGMT (a direct DNA repair protein) has been shown to decrease response to temozolomide and radiotherapy in GBM. Little, however, is known of t...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2016
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| Online Access: | https://eprints.nottingham.ac.uk/36449/ |