Robust anti-nociceptive effects of MAG lipase inhibition in a model of osteoarthritis pain

BACKGROUND AND PURPOSE: Chronic pain is often a symptom of knee osteoarthritis (OA) for which current analgesics are either inadequate, or are associated with serious side effects. The endocannabinoid system may offer alternative targets for pain-relief. We evaluated the effects of a potent and sele...

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Bibliographic Details
Main Authors: Burston, James J., Mapp, Paul I., Sarmad, Sarir, Barrett, David A., Niphakis, Micah J., Cravatt, Benjamin F., Walsh, David A., Chapman, Victoria
Format: Article
Published: Wiley 2016
Online Access:https://eprints.nottingham.ac.uk/36179/