Distinct microenvironmental cues trigger divergent TLR4-mediated immune signalling in macrophages

Macrophages exhibit a phenotypic plasticity that enables them to orchestrate specific immune responses to distinct threats. However, the factors that control macrophage behaviour in a context dependent manner are not well understood. Lipopolysaccharide (LPS) and the extracellular matrix glycoprotein...

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Bibliographic Details
Main Authors: Piccinini, Anna M., Zuliani-Alvarez, Lorena, Lim, Jenny M.P., Midwood, Kim S.
Format: Article
Published: American Association for the Advancement of Science 2016
Online Access:https://eprints.nottingham.ac.uk/35964/