Phosphonium polymethacrylates for siRNA delivery: effect of polymer and RNA structural parameters on polyplex assembly and gene knockdown
Synthetic polymers containing quaternary phosphonium salts are an emerging class of materials for the delivery of oligo/polynucleotides. In this work, cationic phosphonium salt-containing polymethacrylates –and their corresponding ammonium analogues– were synthesized by RAFT polymerization. Both the...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Published: |
American Chemical Society
2015
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| Online Access: | https://eprints.nottingham.ac.uk/35894/ |