Drug-like antagonists of P2Y receptors — from lead identification to drug development

P2Y receptors are expressed in virtually all cells and tissue types and mediate an astonishing array of biological functions, including platelet aggregation, smooth muscle cell proliferation, and immune regulation. The P2Y receptors belong to the G protein-coupled receptor superfamily and are compos...

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Bibliographic Details
Main Authors: Conroy, Sean, Kindon, Nicholas, Kellam, Barrie, Stocks, Michael
Format: Article
Published: American Chemical Society 2016
Online Access:https://eprints.nottingham.ac.uk/35643/