Innate immune recognition of Neisseria meningitidis at the nasopharynx
Neisseria meningitidis is considered as the main suspect behind the majority of meningitis and sepsis cases globally. The major component of the outer membrane in Neisseria, lipooligosaccharide (LOS), is recognized by Toll-like receptor 4 (TLR4), triggering a pro-inflammatory cytokine respon...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2016
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| Online Access: | https://eprints.nottingham.ac.uk/35276/ |