Molecular insights into DNA interference by CRISPR-associated nuclease-helicase Cas3

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Molecular insights into DNA interference by CRISPR-associated nuclease-helicase Cas3

Mobile genetic elements in bacteria are neutralized by a system based on clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) proteins. Type I CRISPR-Cas systems use a “Cascade” ribonucleoprotein complex to guide RNA specifically to complementary sequence i...

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Bibliographic Details
Main Authors:	Gong, Bei, Shin, Minsang, Sun, Jiali, Jung, Che-Hun, Bolt, Edward L., van der oost, John, Kim, Jeong-Sun
Format:	Article
Published:	National Academy of Sciences 2014
Subjects:	Cas3 CRISPR Cascade Bacterial Immunity Cas Proteins
Online Access:	https://eprints.nottingham.ac.uk/35113/

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