Molecular insights into DNA interference by CRISPR-associated nuclease-helicase Cas3
Mobile genetic elements in bacteria are neutralized by a system based on clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) proteins. Type I CRISPR-Cas systems use a “Cascade” ribonucleoprotein complex to guide RNA specifically to complementary sequence i...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Published: |
National Academy of Sciences
2014
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| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/35113/ |