Relative contribution of intramyocellular lipid to whole-body fat oxidation is reduced with age but subsarcolemmal lipid accumulation and insulin resistance are only associated with overweight individuals

Insulin resistance is closely related to intramyocellular lipid (IMCL) accumulation, and both are associated with increasing age. It remains to be determined to what extent perturbations in IMCL metabolism are related to the aging process per se. On two separate occasions, whole-body and muscle insu...

Full description

Bibliographic Details
Main Authors: Chee, Carolyn, Shannon, Chris E., Burns, Aisling, Selby, Anna L., Wilkinson, Daniel, Smith, Kenneth, Greenhaff, Paul L., Stephens, Francis B.
Format: Article
Published: American Diabetes Association 2016
Online Access:https://eprints.nottingham.ac.uk/35101/