Analysis of the functional repertoire of a mutant form of survivin, K129E, which has been linked to lung cancer

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Analysis of the functional repertoire of a mutant form of survivin, K129E, which has been linked to lung cancer

Background Survivin is a protein that is normally present only in G2 and M-phases in somatic cells, however, in cancer cells, it is expressed throughout the cell cycle. A prosurvival factor, survivin is both an inhibitor of apoptosis and an essential mitotic protein, thus it has attracted much atte...

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Bibliographic Details
Main Authors:	Aljaberi, Aysha M., Webster, Jamie R.M., Wheatley, Sally P.
Format:	Article
Published:	BioMed Central 2014
Subjects:	Survivin Borealin Mitosis Cytokinesis Apoptosis Cancer Polymorphism
Online Access:	https://eprints.nottingham.ac.uk/35004/

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