Analysis of the functional repertoire of a mutant form of survivin, K129E, which has been linked to lung cancer
Background Survivin is a protein that is normally present only in G2 and M-phases in somatic cells, however, in cancer cells, it is expressed throughout the cell cycle. A prosurvival factor, survivin is both an inhibitor of apoptosis and an essential mitotic protein, thus it has attracted much atte...
| Main Authors: | , , |
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| Format: | Article |
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BioMed Central
2014
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| Online Access: | https://eprints.nottingham.ac.uk/35004/ |