Stereoselective synthesis of highly substituted tetrahydrofurans by diverted carbene O–H insertion reaction
Copper or rhodium catalyzed reaction of diazocarbonyl compounds with β-hydroxyketones gives highly substituted tetrahydrofurans with excellent diastereoselectivity, under mild conditions, in a single step process that starts as a carbene O–H insertion reaction but is diverted by an intramolecular al...
| Main Authors: | , , , |
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| Format: | Article |
| Published: |
Wiley-VCH Verlag
2015
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| Online Access: | https://eprints.nottingham.ac.uk/34963/ |