Fragment-based discovery of subtype-selective adenosine receptor ligands from homology models
Fragment-based lead discovery (FBLD) holds great promise for drug discovery, but applications to G protein-coupled receptors (GPCRs) have been limited by a lack of sensitive screening techniques and scarce structural information. If virtual screening against homology models of GPCRs could be used to...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Published: |
American Chemical Society
2015
|
| Online Access: | https://eprints.nottingham.ac.uk/34664/ |