Recognition of membrane sterols by polyene antifungals amphotericin B and natamycin, a 13C MAS NMR Study

Recognition of membrane sterols by polyene antifungals amphotericin B and natamycin, a 13C MAS NMR Study

The molecular action of polyene macrolides with antifungal activity, amphotericin B and natamycin, involves recognition of sterols in membranes. Physicochemical and functional studies have contributed details to understanding the interactions between amphotericin B and ergosterol and, to a lesser ex...

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Bibliographic Details
Main Authors: Ciesielski, Filip, Griffin, David C., Loraine, Jessica, Rittig, Michael, Delves-Broughton, Joss, Bonev, Boyan B.
Format: Article
Published: Frontiers Media 2016
Subjects:
Antimicrobials
antifungals
membranes
cholesterol
ergosterol
13C solid state MAS NMR
receptor recognition
Online Access:https://eprints.nottingham.ac.uk/34649/

Internet

https://eprints.nottingham.ac.uk/34649/

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